A Single Dose of Kudzu Extract Reduces Alcohol Consumption in a Binge Drinking Paradigm PMC
Sober living
Puerarin is injected iv in patients to treat coronary heart disease (Gao et al, 2015). Finally, we have just completed a study revealing that puerarin upregulates VMAT2 (dopamine transporter) gene expression, which has been implicated in the etiology of alcoholism (Xiong et al, 2016). Kudzu is one of the earliest medicinal plants used in traditional Chinese medicine.
Osteogenic activity
In spite of the compelling preclinical and clinical evidence of its efficacy, the precise mechanism of action of kudzu in reducing alcohol consumption is not currently known. Prior studies of its antidipsotropic effect have focused on taste-aversion, alterations in alcohol metabolism or effects on neurotransmitters. Overstreet et al.’s (1998) study provides cursory evidence that a taste aversion mechanism is not likely.
What are the recommended dosages of kudzu for alcoholism treatment?
There is some evidence that kudzu root dietary supplements may cause liver injury. One study in mice found that taking 10 mg per day of kudzu root extract for 4 weeks caused liver toxicity (15). Furthermore, the men who took kudzu had fewer heavy drinking days per week and had significantly more consecutive days with no alcohol consumption (2). All participants were recruited following approval by the McLean Hospital Institutional Review Board (IRB).
Does microwaving food make it less healthy?
Before embarking on a journey with kudzu as a potential remedy for alcoholism, it is crucial to consult with a healthcare professional. The absence of standardized dosages and recommended administration methods for kudzu necessitates expert guidance. Your healthcare provider can help determine the most suitable approach based on your unique kudzu extract for alcoholism circumstances. However, these studies were conducted on lone individuals drinking within highly controlled laboratory conditions. Kudzu has been shown to be effective in reducing alcohol cravings and consumption in the short term. However, more research is needed to determine its long-term effectiveness in promoting alcoholism recovery.
- Two hours before the first visit, we gave both sub-groups a pill – neither group knew whether they were getting the supplement or the placebo.
- Quantitative analysis of ethanol levels was performed by gas chromatography with flame ionization detection (GC/FID) (Hewlett-Packard model 5890 series II equipped with a model 18593B autosampler) (Penetar et al., 2008).
- Research has demonstrated that taking a kudzu extract prior to drinking can reduce alcoholic intake by between 30 and 50%.
- Alcohol drinking was not completely eliminated by kudzu extract in the present study, but was reduced from baseline drinking by an average of 45% over the four weeks of treatment.
- Another study found that people who took puerarin, an isoflavone extract from the kudzu plant, prior to drinking took longer to consume alcoholic beverages (3).
Cardiovascular effects
Remember that every individual’s journey to recovery is unique, and what works for one person may not work for another. For those seeking help with alcohol addiction, valuable resources are available online. One such resource is AlcoholAwareness.org, which offers a wealth of information, support, and guidance for individuals and their families dealing with alcoholism. Until the effects of kudzu can be quantified properly in a larger study, then, and a standardised product is available on the market with the THR mark, it’s not something we can recommend you take.
For instance, it may reduce the effectiveness of birth control due to its estrogenic effects (8, 17). Today, the most popular ways to use kudzu root are as an herbal supplement or a root tea. For over 2,000 years, people have used kudzu root in traditional Chinese medicine for purposes like treating fevers, diarrhea, and even diabetes and heart disease (1). More recently, kudzu root https://ecosoberhouse.com/ has made its way to Western countries as an herbal supplement. Various herbs and combinations of herbs are reported to be effective in reducing cravings, but in general, no studies have been conducted to prove their effectiveness. Various herbs and combinations of herbs are reported to be effective in reducing cravings, but in general, no studies have proven their effectiveness.
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